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Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice

BACKGROUND: Neuroinflammation contributes to the pathophysiology of acute CNS injury, including traumatic brain injury (TBI). Although prostaglandin lipid mediators of inflammation contribute to a variety of inflammatory responses, their importance in neuroinflammation is not clear. There are confli...

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Detalles Bibliográficos
Autores principales: Kelso, Matthew L, Scheff, Stephen W, Pauly, James R, Loftin, Charles D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751761/
https://www.ncbi.nlm.nih.gov/pubmed/19719848
http://dx.doi.org/10.1186/1471-2202-10-108