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Primary open angle glaucoma in a Caucasian population is associated with the p53 codon 72 polymorphism

PURPOSE: Apoptosis has been implicated as the mechanism for retinal ganglion cell death in primary open-angle glaucoma (POAG), a complex neurodegenerative disease. There have been inconsistent reports regarding increased risk of POAG and a polymorphism (Arg72Pro) within the tumor suppressor gene, p5...

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Detalles Bibliográficos
Autores principales: Daugherty, Christopher L., Curtis, Hilda, Realini, Tony, Charlton, Judie F., Zareparsi, Sepideh
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751801/
https://www.ncbi.nlm.nih.gov/pubmed/19784392