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Investigating Bacterial Sources of Toxicity as an Environmental Contributor to Dopaminergic Neurodegeneration

Parkinson disease (PD) involves progressive neurodegeneration, including loss of dopamine (DA) neurons from the substantia nigra. Select genes associated with rare familial forms of PD function in cellular pathways, such as the ubiquitin-proteasome system (UPS), involved in protein degradation. The...

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Detalles Bibliográficos
Autores principales: Caldwell, Kim A., Tucci, Michelle L., Armagost, Jafa, Hodges, Tyler W., Chen, Jue, Memon, Shermeen B., Blalock, Jeana E., DeLeon, Susan M., Findlay, Robert H., Ruan, Qingmin, Webber, Philip J., Standaert, David G., Olson, Julie B., Caldwell, Guy A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751819/
https://www.ncbi.nlm.nih.gov/pubmed/19806188
http://dx.doi.org/10.1371/journal.pone.0007227