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Inherited Glutathione Reductase Deficiency and Plasmodium falciparum Malaria—A Case Study
In Plasmodium falciparum-infected red blood cells (RBCs), the flavoenzyme glutathione reductase (GR) regenerates reduced glutathione, which is essential for antioxidant defense. GR utilizes NADPH produced in the pentose phosphate shunt by glucose-6-phosphate dehydrogenase (G6PD). Thus, conditions af...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751828/ https://www.ncbi.nlm.nih.gov/pubmed/19806191 http://dx.doi.org/10.1371/journal.pone.0007303 |