Inherited Glutathione Reductase Deficiency and Plasmodium falciparum Malaria—A Case Study

In Plasmodium falciparum-infected red blood cells (RBCs), the flavoenzyme glutathione reductase (GR) regenerates reduced glutathione, which is essential for antioxidant defense. GR utilizes NADPH produced in the pentose phosphate shunt by glucose-6-phosphate dehydrogenase (G6PD). Thus, conditions af...

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Detalles Bibliográficos
Autores principales: Gallo, Valentina, Schwarzer, Evelin, Rahlfs, Stefan, Schirmer, R. Heiner, van Zwieten, Rob, Roos, Dirk, Arese, Paolo, Becker, Katja
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751828/
https://www.ncbi.nlm.nih.gov/pubmed/19806191
http://dx.doi.org/10.1371/journal.pone.0007303

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