Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation

Interleukin 17 (IL-17)-producing CD4(+) T (T(H)-17) cells share a developmental relationship with FoxP3(+) regulatory T (T(reg)) cells. Here we show that a T(H)-17 population differentiates within the thymus in a manner influenced by self-antigen recognition, and by the cytokines IL-6 and transformi...

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Detalles Bibliográficos
Autores principales: Marks, Benjamin R., Nowyhed, Heba N., Choi, Jin-Young, Poholek, Amanda C., Odegard, Jared M., Flavell, Richard A., Craft, Joe
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751862/
https://www.ncbi.nlm.nih.gov/pubmed/19734905
http://dx.doi.org/10.1038/ni.1783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751862/
https://www.ncbi.nlm.nih.gov/pubmed/19734905
http://dx.doi.org/10.1038/ni.1783

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