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Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

Jmjd3, a JmjC family histone demethylase, is induced by the transcription factor NF-kB in response to microbial stimuli. Jmjd3 erases H3K27me3, a histone mark associated with transcriptional repression and involved in lineage determination. However, the specific contribution of Jmjd3 induction and H...

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Detalles Bibliográficos
Autores principales: De Santa, Francesca, Narang, Vipin, Yap, Zhei Hwee, Tusi, Betsabeh Khoramian, Burgold, Thomas, Austenaa, Liv, Bucci, Gabriele, Caganova, Marieta, Notarbartolo, Samuele, Casola, Stefano, Testa, Giuseppe, Sung, Wing-Kin, Wei, Chia-Lin, Natoli, Gioacchino
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752025/
https://www.ncbi.nlm.nih.gov/pubmed/19779457
http://dx.doi.org/10.1038/emboj.2009.271