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The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP

Vaults are ubiquitous ribonucleoprotein complexes involved in a diversity of cellular processes, including multidrug resistance, transport mechanisms and signal transmission. The vault particle shows a barrel-shaped structure organized in two identical moieties, each consisting of 39 copies of the m...

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Detalles Bibliográficos
Autores principales: Querol-Audí, Jordi, Casañas, Arnau, Usón, Isabel, Luque, Daniel, Castón, José R, Fita, Ignasi, Verdaguer, Nuria
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752026/
https://www.ncbi.nlm.nih.gov/pubmed/19779459
http://dx.doi.org/10.1038/emboj.2009.274