Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

Type 1 diabetes (T1D) may result from a breakdown in peripheral tolerance that is partially controlled by peripheral tissue antigen (PTA) expression in lymph nodes. Here we show that the transcriptional regulator deformed epidermal autoregulatory factor 1 (Deaf1) controls PTA gene expression in the...

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Detalles Bibliográficos
Autores principales: Yip, Linda, Su, Leon, Sheng, Deqiao, Chang, Pearl, Atkinson, Mark, Czesak, Margaret, Albert, Paul R., Collier, Ai-Ris, Turley, Shannon J., Fathman, C. Garrison, Creusot, Rémi J.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752139/
https://www.ncbi.nlm.nih.gov/pubmed/19668219
http://dx.doi.org/10.1038/ni.1773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752139/
https://www.ncbi.nlm.nih.gov/pubmed/19668219
http://dx.doi.org/10.1038/ni.1773

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