MUC1 Limits Helicobacter pylori Infection both by Steric Hindrance and by Acting as a Releasable Decoy

The bacterium Helicobacter pylori can cause peptic ulcer disease, gastric adenocarcinoma and MALT lymphoma. The cell-surface mucin MUC1 is a large glycoprotein which is highly expressed on the mucosal surface and limits the density of H. pylori in a murine infection model. We now demonstrate that by...

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Detalles Bibliográficos
Autores principales: Lindén, Sara K., Sheng, Yong H., Every, Alison L., Miles, Kim M., Skoog, Emma C., Florin, Timothy H. J., Sutton, Philip, McGuckin, Michael A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752161/
https://www.ncbi.nlm.nih.gov/pubmed/19816567
http://dx.doi.org/10.1371/journal.ppat.1000617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752161/
https://www.ncbi.nlm.nih.gov/pubmed/19816567
http://dx.doi.org/10.1371/journal.ppat.1000617

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