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Muscle-Specific Adaptations, Impaired Oxidative Capacity and Maintenance of Contractile Function Characterize Diet-Induced Obese Mouse Skeletal Muscle

BACKGROUND: The effects of diet-induced obesity on skeletal muscle function are largely unknown, particularly as it relates to changes in oxidative metabolism and morphology. PRINCIPAL FINDINGS: Compared to control fed mice, mice fed a high fat diet (HFD; 60% kcal: fat) for 8 weeks displayed increas...

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Detalles Bibliográficos
Autores principales: Shortreed, Karin E., Krause, Matthew P., Huang, Julianna H., Dhanani, Dili, Moradi, Jasmin, Ceddia, Rolando B., Hawke, Thomas J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752162/
https://www.ncbi.nlm.nih.gov/pubmed/19806198
http://dx.doi.org/10.1371/journal.pone.0007293