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Activation of innate immune antiviral response by NOD2

Pattern recognition receptors (PRRs) including Toll-like receptors (TLRs) and RIG like helicase (RLH) receptors are involved in innate immune antiviral responses. Here we show that nucleotide-binding oligomerization domain 2 (NOD2) can also function as a cytoplasmic viral PRR by triggering activatio...

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Detalles Bibliográficos
Autores principales: Sabbah, Ahmed, Chang, Te Hung, Harnack, Rosalinda, Frohlich, Victoria, Tominaga, Kaoru, Dube, Peter H., Xiang, Yan, Bose, Santanu
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752345/
https://www.ncbi.nlm.nih.gov/pubmed/19701189
http://dx.doi.org/10.1038/ni.1782