Gene expression profiling of human alveolar macrophages infected by B. anthracis spores demonstrates TNF-α and NF-κb are key components of the innate immune response to the pathogen

BACKGROUND: Bacillus anthracis, the etiologic agent of anthrax, has recently been used as an agent of bioterrorism. The innate immune system initially appears to contain the pathogen at the site of entry. Because the human alveolar macrophage (HAM) plays a key role in lung innate immune responses, s...

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Detalles Bibliográficos
Autores principales: Dozmorov, Mikhail, Wu, Wenxin, Chakrabarty, Kaushik, Booth, J Leland, Hurst, Robert E, Coggeshall, K Mark, Metcalf, Jordan P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752459/
https://www.ncbi.nlm.nih.gov/pubmed/19744333
http://dx.doi.org/10.1186/1471-2334-9-152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752459/
https://www.ncbi.nlm.nih.gov/pubmed/19744333
http://dx.doi.org/10.1186/1471-2334-9-152

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