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Knowledge-guided inference of domain–domain interactions from incomplete protein–protein interaction networks

Motivation: Protein-protein interactions (PPIs), though extremely valuable towards a better understanding of protein functions and cellular processes, do not provide any direct information about the regions/domains within the proteins that mediate the interaction. Most often, it is only a fraction o...

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Detalles Bibliográficos
Autores principales: Liu, Mei, Chen, Xue-wen, Jothi, Raja
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752622/
https://www.ncbi.nlm.nih.gov/pubmed/19667081
http://dx.doi.org/10.1093/bioinformatics/btp480