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Simulations of Tubulin Sheet Polymers as Possible Structural Intermediates in Microtubule Assembly
The microtubule assembly process has been extensively studied, but the underlying molecular mechanism remains poorly understood. The structure of an artificially generated sheet polymer that alternates two types of lateral contacts and that directly converts into microtubules, has been proposed to c...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752796/ https://www.ncbi.nlm.nih.gov/pubmed/19806219 http://dx.doi.org/10.1371/journal.pone.0007291 |