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Simulations of Tubulin Sheet Polymers as Possible Structural Intermediates in Microtubule Assembly

The microtubule assembly process has been extensively studied, but the underlying molecular mechanism remains poorly understood. The structure of an artificially generated sheet polymer that alternates two types of lateral contacts and that directly converts into microtubules, has been proposed to c...

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Detalles Bibliográficos
Autores principales: Wu, Zhanghan, Wang, Hong-Wei, Mu, Weihua, Ouyang, Zhongcan, Nogales, Eva, Xing, Jianhua
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752796/
https://www.ncbi.nlm.nih.gov/pubmed/19806219
http://dx.doi.org/10.1371/journal.pone.0007291