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Transmissibility of Atypical Scrapie in Ovine Transgenic Mice: Major Effects of Host Prion Protein Expression and Donor Prion Genotype

Atypical scrapie or Nor98 has been identified as a transmissible spongiform encephalopathy (TSE) that is clearly distinguishable from classical scrapie and BSE, notably regarding the biochemical features of the protease-resistant prion protein PrP(res) and the genetic factors involved in susceptibil...

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Detalles Bibliográficos
Autores principales: Arsac, Jean-Noël, Bétemps, Dominique, Morignat, Eric, Féraudet, Cécile, Bencsik, Anna, Aubert, Denise, Grassi, Jacques, Baron, Thierry
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752806/
https://www.ncbi.nlm.nih.gov/pubmed/19806224
http://dx.doi.org/10.1371/journal.pone.0007300