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Renal Effects of Aliskiren Compared With and in Combination With Irbesartan in Patients With Type 2 Diabetes, Hypertension, and Albuminuria

OBJECTIVE: We investigated whether the antiproteinuric effect of the direct renin inhibitor aliskiren is comparable to that of irbesartan and the effect of the combination. RESEARCH DESIGN AND METHODS: This was a double-blind, randomized, crossover trial. After a 1-month washout period, 26 patients...

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Detalles Bibliográficos
Autores principales: Persson, Frederik, Rossing, Peter, Reinhard, Henrik, Juhl, Tina, Stehouwer, Coen D.A., Schalkwijk, Casper, Danser, A.H. Jan, Boomsma, Frans, Frandsen, Erik, Parving, Hans-Henrik
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752919/
https://www.ncbi.nlm.nih.gov/pubmed/19587362
http://dx.doi.org/10.2337/dc09-0168