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Antimicrobial Activity of Human Prion Protein Is Mediated by Its N-Terminal Region
BACKGROUND: Cellular prion-related protein (PrP(c)) is a cell-surface protein that is ubiquitously expressed in the human body. The multifunctionality of PrP(c), and presence of an exposed cationic and heparin-binding N-terminus, a feature characterizing many antimicrobial peptides, made us hypotesi...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752989/ https://www.ncbi.nlm.nih.gov/pubmed/19809501 http://dx.doi.org/10.1371/journal.pone.0007358 |