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Virus-Induced Chaperone-Enriched (VICE) Domains Function as Nuclear Protein Quality Control Centers during HSV-1 Infection

Virus-Induced Chaperone-Enriched (VICE) domains form adjacent to nuclear viral replication compartments (RC) during the early stages of HSV-1 infection. Between 2 and 3 hours post infection at a MOI of 10, host protein quality control machinery such as molecular chaperones (e.g. Hsc70), the 20S prot...

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Detalles Bibliográficos
Autores principales: Livingston, Christine M., Ifrim, Marius F., Cowan, Ann E., Weller, Sandra K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752995/
https://www.ncbi.nlm.nih.gov/pubmed/19816571
http://dx.doi.org/10.1371/journal.ppat.1000619