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Role of ERO1-α–mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress–induced apoptosis

Endoplasmic reticulum (ER) stress–induced apoptosis is involved in many diseases, but the mechanisms linking ER stress to apoptosis are incompletely understood. Based on roles for C/EPB homologous protein (CHOP) and ER calcium release in apoptosis, we hypothesized that apoptosis involves the activat...

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Detalles Bibliográficos
Autores principales: Li, Gang, Mongillo, Marco, Chin, King-Tung, Harding, Heather, Ron, David, Marks, Andrew R., Tabas, Ira
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753154/
https://www.ncbi.nlm.nih.gov/pubmed/19752026
http://dx.doi.org/10.1083/jcb.200904060