Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion

Two dynamin-related protein (DRP) families are essential for fusion of the outer and inner mitochondrial membranes, Fzo1 (yeast)/Mfn1/Mfn2 (mammals) and Mgm1 (yeast)/Opa1 (mammals), respectively. Fzo1/Mfns possess two medial transmembrane domains, which place their critical GTPase and coiled-coil do...

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Detalles Bibliográficos
Autores principales: DeVay, Rachel M., Dominguez-Ramirez, Lenin, Lackner, Laura L., Hoppins, Suzanne, Stahlberg, Henning, Nunnari, Jodi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753158/
https://www.ncbi.nlm.nih.gov/pubmed/19752025
http://dx.doi.org/10.1083/jcb.200906098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753158/
https://www.ncbi.nlm.nih.gov/pubmed/19752025
http://dx.doi.org/10.1083/jcb.200906098

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