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UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans

Small guanosine triphosphatases of the Rab family regulate intracellular vesicular trafficking. Rab2 is highly expressed in the nervous system, yet its function in neurons is unknown. In Caenorhabditis elegans, unc-108/rab-2 mutants have been isolated based on their locomotory defects. We show that...

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Detalles Bibliográficos
Autores principales: Sumakovic, Marija, Hegermann, Jan, Luo, Ling, Husson, Steven J., Schwarze, Katrin, Olendrowitz, Christian, Schoofs, Liliane, Richmond, Janet, Eimer, Stefan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753160/
https://www.ncbi.nlm.nih.gov/pubmed/19797081
http://dx.doi.org/10.1083/jcb.200902096