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The identification and functional implications of human-specific "fixed" amino acid substitutions in the glutamate receptor family
BACKGROUND: The glutamate receptors (GluRs) play a vital role in the mediation of excitatory synaptic transmission in the central nervous system. To clarify the evolutionary dynamics and mechanisms of the GluR genes in the lineage leading to humans, we determined the complete sequences of the coding...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753569/ https://www.ncbi.nlm.nih.gov/pubmed/19737383 http://dx.doi.org/10.1186/1471-2148-9-224 |