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The identification and functional implications of human-specific "fixed" amino acid substitutions in the glutamate receptor family

BACKGROUND: The glutamate receptors (GluRs) play a vital role in the mediation of excitatory synaptic transmission in the central nervous system. To clarify the evolutionary dynamics and mechanisms of the GluR genes in the lineage leading to humans, we determined the complete sequences of the coding...

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Detalles Bibliográficos
Autores principales:	Goto, Hiroki, Watanabe, Kazunori, Araragi, Naozumi, Kageyama, Rui, Tanaka, Kunika, Kuroki, Yoko, Toyoda, Atsushi, Hattori, Masahira, Sakaki, Yoshiyuki, Fujiyama, Asao, Fukumaki, Yasuyuki, Shibata, Hiroki
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753569/ https://www.ncbi.nlm.nih.gov/pubmed/19737383 http://dx.doi.org/10.1186/1471-2148-9-224

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