Human Sirt-1: Molecular Modeling and Structure-Function Relationships of an Unordered Protein

BACKGROUND: Sirt-1 is a NAD+-dependent nuclear deacetylase of 747 residues that in mammals is involved in various important metabolic pathways, such as glucose metabolism and insulin secretion, and often works on many different metabolic substrates as a multifunctional protein. Sirt-1 down-regulates...

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Detalles Bibliográficos
Autores principales: Autiero, Ida, Costantini, Susan, Colonna, Giovanni
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753774/
https://www.ncbi.nlm.nih.gov/pubmed/19806227
http://dx.doi.org/10.1371/journal.pone.0007350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753774/
https://www.ncbi.nlm.nih.gov/pubmed/19806227
http://dx.doi.org/10.1371/journal.pone.0007350

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