Cargando…
Human Sirt-1: Molecular Modeling and Structure-Function Relationships of an Unordered Protein
BACKGROUND: Sirt-1 is a NAD+-dependent nuclear deacetylase of 747 residues that in mammals is involved in various important metabolic pathways, such as glucose metabolism and insulin secretion, and often works on many different metabolic substrates as a multifunctional protein. Sirt-1 down-regulates...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753774/ https://www.ncbi.nlm.nih.gov/pubmed/19806227 http://dx.doi.org/10.1371/journal.pone.0007350 |