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Protein kinase DYRK2 is an E3-ligase specific molecular assembler
Protein kinases play central roles in diverse cellular signal transduction pathways via their substrate phosphorylation. In this study, we discover that a protein kinase DYRK2 has unexpected role as a molecular assembler for an E3-ubiquitin ligase complex. DYRK2 associates with an E3 ligase complex...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754075/ https://www.ncbi.nlm.nih.gov/pubmed/19287380 http://dx.doi.org/10.1038/ncb1848 |