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Lacosamide as treatment for partial epilepsy: mechanisms of action, pharmacology, effects, and safety
Lacosamide (LCM) is a novel agent that has been developed as an antiepileptic drug. In vitro studies suggest that LCM modulates voltage-gated sodium channels by enhancing their slow inactivation. In addition, LCM seems to interact with collapsin-response mediator protein 2 and thus may mediate neuro...
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| Formato: | Texto |
| Lenguaje: | English |
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Dove Medical Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754090/ https://www.ncbi.nlm.nih.gov/pubmed/19816574 |