Nanoparticle-Delivered Multimeric Soluble CD40L DNA Combined with Toll-Like Receptor Agonists as a Treatment for Melanoma

Stimulation of CD40 or Toll-Like Receptors (TLR) has potential for tumor immunotherapy. Combinations of CD40 and TLR stimulation can be synergistic, resulting in even stronger dendritic cell (DC) and CD8+ T cell responses. To evaluate such combinations, established B16F10 melanoma tumors were inject...

Descripción completa

Detalles Bibliográficos
Autores principales: Stone, Geoffrey W., Barzee, Suzanne, Snarsky, Victoria, Santucci, Camila, Tran, Brian, Langer, Robert, Zugates, Gregory T., Anderson, Daniel G., Kornbluth, Richard S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754331/
https://www.ncbi.nlm.nih.gov/pubmed/19812695
http://dx.doi.org/10.1371/journal.pone.0007334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754331/
https://www.ncbi.nlm.nih.gov/pubmed/19812695
http://dx.doi.org/10.1371/journal.pone.0007334

Ejemplares similares