Cancer Genomics Identifies Regulatory Gene Networks Associated with the Transition from Dysplasia to Advanced Lung Adenocarcinomas Induced by c-Raf-1

BACKGROUND: Lung cancer is a leading cause of cancer morbidity. To improve an understanding of molecular causes of disease a transgenic mouse model was investigated where targeted expression of the serine threonine kinase c-Raf to respiratory epithelium induced initialy dysplasia and subsequently ad...

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Detalles Bibliográficos
Autores principales: Rohrbeck, Astrid, Borlak, Jürgen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754338/
https://www.ncbi.nlm.nih.gov/pubmed/19812696
http://dx.doi.org/10.1371/journal.pone.0007315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754338/
https://www.ncbi.nlm.nih.gov/pubmed/19812696
http://dx.doi.org/10.1371/journal.pone.0007315

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