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Amino acid residues 201-205 in C-terminal acidic tail region plays a crucial role in antibacterial activity of HMGB1

BACKGROUND: Antibacterial activity is a novel function of high-mobility group box 1 (HMGB1). However, the functional site for this new effect is presently unknown. METHODS AND RESULTS: In this study, recombinant human HMGB1 A box and B box (rHMGB1 A box, rHMGB1 B box), recombinant human HMGB1 (rHMGB...

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Detalles Bibliográficos
Autores principales: Gong, Wei, Li, Yuan, Chao, Fan, Huang, Gang, He, Fengtian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754419/
https://www.ncbi.nlm.nih.gov/pubmed/19751520
http://dx.doi.org/10.1186/1423-0127-16-83