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Isomer-specific effects of CLA on gene expression in human adipose tissue depending on PPARγ2 P12A polymorphism: a double blind, randomized, controlled cross-over study

BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)γ is a key regulator in adipose tissue. The rare variant Pro12Ala of PPARγ2 is associated with a decreased risk of insulin resistance. Being dietary PPARγ ligands, conjugated linoleic acids (CLAs) received considerable attention because of...

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Detalles Bibliográficos
Autores principales: Herrmann, J, Rubin, D, Häsler, R, Helwig, U, Pfeuffer, M, Auinger, A, Laue, C, Winkler, P, Schreiber, S, Bell, D, Schrezenmeir, J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754469/
https://www.ncbi.nlm.nih.gov/pubmed/19689798
http://dx.doi.org/10.1186/1476-511X-8-35