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The Production of Antibody by Invading B Cells Is Required for the Clearance of Rabies Virus from the Central Nervous System
BACKGROUND: The pathogenesis of rabies is associated with the inability to deliver immune effectors across the blood-brain barrier and to clear virulent rabies virus from CNS tissues. However, the mechanisms that facilitate immune effector entry into CNS tissues are induced by infection with attenua...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754506/ https://www.ncbi.nlm.nih.gov/pubmed/19806203 http://dx.doi.org/10.1371/journal.pntd.0000535 |