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The Production of Antibody by Invading B Cells Is Required for the Clearance of Rabies Virus from the Central Nervous System

BACKGROUND: The pathogenesis of rabies is associated with the inability to deliver immune effectors across the blood-brain barrier and to clear virulent rabies virus from CNS tissues. However, the mechanisms that facilitate immune effector entry into CNS tissues are induced by infection with attenua...

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Detalles Bibliográficos
Autores principales: Hooper, D. Craig, Phares, Timothy W., Fabis, Marzena J., Roy, Anirban
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754506/
https://www.ncbi.nlm.nih.gov/pubmed/19806203
http://dx.doi.org/10.1371/journal.pntd.0000535