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Coexistence of Flexibility and Stability of Proteins: An Equation of State

We consider a recently suggested “equation of state” for natively folded proteins, and verify its validity for a set of about 5800 proteins. The equation is based on a fractal viewpoint of proteins, on a generalization of the Landau-Peierls instability, and on a marginal stability criterion. The lat...

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Detalles Bibliográficos
Autores principales: de Leeuw, Marina, Reuveni, Shlomi, Klafter, Joseph, Granek, Rony
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754529/
https://www.ncbi.nlm.nih.gov/pubmed/19816577
http://dx.doi.org/10.1371/journal.pone.0007296