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A Man-Made ATP-Binding Protein Evolved Independent of Nature Causes Abnormal Growth in Bacterial Cells

Recent advances in de novo protein evolution have made it possible to create synthetic proteins from unbiased libraries that fold into stable tertiary structures with predefined functions. However, it is not known whether such proteins will be functional when expressed inside living cells or how a h...

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Detalles Bibliográficos
Autores principales: Stomel, Joshua M., Wilson, James W., León, Megan A., Stafford, Phillip, Chaput, John C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754611/
https://www.ncbi.nlm.nih.gov/pubmed/19812699
http://dx.doi.org/10.1371/journal.pone.0007385