Initiation of myoblast/brown fat switch through a PRDM16-C/EBP-β transcriptional complex

Brown adipose cells are specialized to dissipate chemical energy in the form of heat, as a physiological defense against cold and obesity1. PRDM16 (PRD1-BF1-RIZ1 homologous domain containing 16) is a 140 kDa zinc finger protein that robustly induces brown fat determination and differentiation2. Rece...

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Detalles Bibliográficos
Autores principales: Kajimura, Shingo, Seale, Patrick, Kubota, Kazuishi, Lunsford, Elaine, Frangioni, John V., Gygi, Steven P., Spiegelman, Bruce M.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754867/
https://www.ncbi.nlm.nih.gov/pubmed/19641492
http://dx.doi.org/10.1038/nature08262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754867/
https://www.ncbi.nlm.nih.gov/pubmed/19641492
http://dx.doi.org/10.1038/nature08262

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