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Modeling “psychosis” in vitro by inducing disordered neuronal network activity in cortical brain slices

INTRODUCTION: Dysregulation of neuronal networks has been suggested to underlie the cognitive and perceptual abnormalities observed schizophrenia. DISCUSSIONS: An in vitro model of psychosis is proposed based on the two different approaches to cause aberrant network activity in layer V pyramidal cel...

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Detalles Bibliográficos
Autor principal: Aghajanian, George K.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755104/
https://www.ncbi.nlm.nih.gov/pubmed/19241062
http://dx.doi.org/10.1007/s00213-009-1484-9