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Nicotine Binding to Brain Receptors Requires a Strong Cation-π Interaction
Nicotine addiction begins with high-affinity binding of nicotine to acetylcholine (ACh) receptors in the brain. The end result is over 4,000,000 smoking-related deaths annually worldwide and the largest source of preventable mortality in developed countries. Stress reduction, pleasure, improved cogn...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755585/ https://www.ncbi.nlm.nih.gov/pubmed/19252481 http://dx.doi.org/10.1038/nature07768 |