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Towards a target label-free suboptimum oligonucleotide displacement-based detection system

A novel method for the future development of label-free DNA sensors is proposed here. The approach is based on the displacement of a labelled suboptimum mutated oligonucleotide hybridised with the immobilised biotin-capture probe. The target fully complementary to the biotin-capture probe can displa...

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Detalles Bibliográficos
Autores principales: Mir, Mònica, Lozano-Sánchez, Pablo, Katakis, Ioanis
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755782/
https://www.ncbi.nlm.nih.gov/pubmed/18454283
http://dx.doi.org/10.1007/s00216-008-2119-4