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Towards a target label-free suboptimum oligonucleotide displacement-based detection system
A novel method for the future development of label-free DNA sensors is proposed here. The approach is based on the displacement of a labelled suboptimum mutated oligonucleotide hybridised with the immobilised biotin-capture probe. The target fully complementary to the biotin-capture probe can displa...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755782/ https://www.ncbi.nlm.nih.gov/pubmed/18454283 http://dx.doi.org/10.1007/s00216-008-2119-4 |