Enhancement of toxin- and virus-neutralizing capacity of single-domain antibody fragments by N-glycosylation

Single-domain antibody fragments (VHHs) have several beneficial properties as compared to conventional antibody fragments. However, their small size complicates their toxin- and virus-neutralizing capacity. We isolated 27 VHHs binding Escherichia coli heat-labile toxin and expressed these in Sacchar...

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Detalles Bibliográficos
Autores principales: Harmsen, M. M., van Solt, C. B., Fijten, H. P. D.
Formato: Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2009
Materias:
Biotechnologically Relevant Enzymes and Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755796/
https://www.ncbi.nlm.nih.gov/pubmed/19455325
http://dx.doi.org/10.1007/s00253-009-2029-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755796/
https://www.ncbi.nlm.nih.gov/pubmed/19455325
http://dx.doi.org/10.1007/s00253-009-2029-1

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