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Role of pICLn in Methylation of Sm Proteins by PRMT5

pICln is an essential, highly conserved 26-kDa protein whose functions include binding to Sm proteins in the cytoplasm of human cells and mediating the ordered and regulated assembly of the cell's RNA-splicing machinery by the survival motor neurons complex. pICln also interacts with PRMT5, the...

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Detalles Bibliográficos
Autores principales: Pesiridis, G. Scott, Diamond, Evan, Van Duyne, Gregory D.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755859/
https://www.ncbi.nlm.nih.gov/pubmed/19520849
http://dx.doi.org/10.1074/jbc.M109.015578