Interaction between the Transactivation Domain of p53 and PC4 Exemplifies Acidic Activation Domains as Single-stranded DNA Mimics

The tumor suppressor p53 regulates cell cycle arrest and apoptosis by transactivating several genes that are critical for these processes. The transcriptional activity of p53 is often regulated by post-translational modifications and its interactions with various transcriptional coactivators. Here w...

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Detalles Bibliográficos
Autores principales: Rajagopalan, Sridharan, Andreeva, Antonina, Teufel, Daniel P., Freund, Stefan M., Fersht, Alan R.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Transcription, Chromatin, and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755895/
https://www.ncbi.nlm.nih.gov/pubmed/19525231
http://dx.doi.org/10.1074/jbc.M109.006429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755895/
https://www.ncbi.nlm.nih.gov/pubmed/19525231
http://dx.doi.org/10.1074/jbc.M109.006429

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