The Effects of Nitroxyl (HNO) on Soluble Guanylate Cyclase Activity: INTERACTIONS AT FERROUS HEME AND CYSTEINE THIOLS

It has been previously proposed that nitric oxide (NO) is the only biologically relevant nitrogen oxide capable of activating the enzyme soluble guanylate cyclase (sGC). However, recent reports implicate HNO as another possible activator of sGC. Herein, we examine the affect of HNO donors on the act...

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Detalles Bibliográficos
Autores principales: Miller, Thomas W., Cherney, Melisa M., Lee, Andrea J., Francoleon, Nestor E., Farmer, Patrick J., King, S. Bruce, Hobbs, Adrian J., Miranda, Katrina M., Burstyn, Judith N., Fukuto, Jon M.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Enzyme Catalysis and Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755905/
https://www.ncbi.nlm.nih.gov/pubmed/19531488
http://dx.doi.org/10.1074/jbc.M109.014282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755905/
https://www.ncbi.nlm.nih.gov/pubmed/19531488
http://dx.doi.org/10.1074/jbc.M109.014282

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