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Interactions among the Epidermal Growth Factor-like Modules of Thrombospondin-1

Epidermal growth factor (EGF)-like modules are defined in part by six cysteines joined by disulfides in a 1–3, 2–4, and 5–6 pattern. Thrombospondin-1 (TSP-1) is a multimodular glycoprotein with three EGF-like modules, E1, E2, and E3, arranged in tandem. These modules likely propagate conformational...

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Detalles Bibliográficos
Autores principales: Liu, Yuanyuan, Annis, Douglas S., Mosher, Deane F.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755945/
https://www.ncbi.nlm.nih.gov/pubmed/19531495
http://dx.doi.org/10.1074/jbc.M109.026120