Wolbachia Lipoprotein Stimulates Innate and Adaptive Immunity through Toll-like Receptors 2 and 6 to Induce Disease Manifestations of Filariasis

Wolbachia endosymbiotic bacteria have been implicated in the inflammatory pathogenesis of filariasis. Inflammation induced by Brugia malayi female worm extract (BMFE) is dependent on Toll-like receptors 2 and 6 (TLR2/6) with only a partial requirement for TLR1. Removal of Wolbachia, lipids, or prote...

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Detalles Bibliográficos
Autores principales: Turner, Joseph D., Langley, R. Stuart, Johnston, Kelly L., Gentil, Katrin, Ford, Louise, Wu, Bo, Graham, Maia, Sharpley, Faye, Slatko, Barton, Pearlman, Eric, Taylor, Mark J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755959/
https://www.ncbi.nlm.nih.gov/pubmed/19458089
http://dx.doi.org/10.1074/jbc.M901528200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755959/
https://www.ncbi.nlm.nih.gov/pubmed/19458089
http://dx.doi.org/10.1074/jbc.M901528200

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