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MyosinV controls PTEN function and neuronal cell size

The tumour suppressor PTEN can inhibit proliferation and migration as well as control cell growth in different cell types1. PTEN functions predominately as a lipid phsophatase, converting PI(3,4,5)P(3) to PI(4,5)P(2), thereby antagonizing PI3K (Phosphoinositide 3-kinase) and its established downstre...

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Detalles Bibliográficos
Autores principales: van Diepen, Michiel, Parsons, Maddy, Downes, C. Peter, Leslie, Nicholas R., Hindges, Robert, Eickholt, Britta J
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756284/
https://www.ncbi.nlm.nih.gov/pubmed/19767745
http://dx.doi.org/10.1038/ncb1961