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Oncogenes do not Fully Override Cell-intrinsic Traits: Pronounced Impact of the Cellular Programme

Overexpression of p53 tumor suppressor protein in malignant cells induces cell cycle arrest, or alternatively, apoptosis thereby indicating that additional factors may contribute to the p53-mediated outcome. Comparison of the experimental protocols revealed that the construct encoding wild-type (wt)...

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Detalles Bibliográficos
Autores principales: Węsierska-Gądek, Józefa, Walzi, Eva, Dolečkova, Iva, Schmid, Gerald
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756341/
https://www.ncbi.nlm.nih.gov/pubmed/19731086
http://dx.doi.org/10.1007/s12307-009-0024-9