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Is TEA an inhibitor for human Aquaporin-1?

Excessive water uptake through aquaporins can be life threatening, and disregulation of water permeability causes many diseases. Therefore, reversible aquaporin inhibitors are highly desired. In this paper, we identified the binding site for tetraethylammonium (TEA) of the membrane water channel aqu...

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Detalles Bibliográficos
Autores principales: Müller, E. Matthias, Hub, Jochen S., Grubmüller, Helmut, de Groot, Bert L.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756347/
https://www.ncbi.nlm.nih.gov/pubmed/18196268
http://dx.doi.org/10.1007/s00424-007-0422-0