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Is TEA an inhibitor for human Aquaporin-1?
Excessive water uptake through aquaporins can be life threatening, and disregulation of water permeability causes many diseases. Therefore, reversible aquaporin inhibitors are highly desired. In this paper, we identified the binding site for tetraethylammonium (TEA) of the membrane water channel aqu...
Autores principales: | Müller, E. Matthias, Hub, Jochen S., Grubmüller, Helmut, de Groot, Bert L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756347/ https://www.ncbi.nlm.nih.gov/pubmed/18196268 http://dx.doi.org/10.1007/s00424-007-0422-0 |
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